Evaluation of Fungal Infections in Burn Patients at Ali-ebn AbiTalib Hospital in Zahedan

Document Type : Original Article

Authors

1 Department of Surgery, Clinical Immunology Research Center, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

2 Department of Surgery, Student Research Committee, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

3 Department of Medical Laboratory Sciences, Infectious Diseases and Tropical Medicine Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Diseases, School of ParaMedicine, Zahedan University of Medical Sciences, Zahedan, Iran.

Abstract

Background: Burns are the leading cause of disability and mortality in the world, which has led to serious economic and social consequences. 

Objectives: The present study aimed to investigate fungal infections in burn patients admitted to Ali-ebn Abitalib Hospital in Zahedan.

Methods: This study was conducted from April 2023 to October 2023. The research population was 113 burn patients admitted to Ali-ebn Abitalib Hospital. Data was collected by recording demographic data, sampling lesions suspected of fungal infection, and laboratory tests. All samples were recognized using phenotypic methods such as microscopy and culture on Sabouraud dextrose agar with chloramphenicol. The data was analyzed using SPSS software version 26.

Results: About 13.3% of the studied burn patients had a positive fungal culture. The most common fungus grown in burn patients was Candida albicans/C. dubliniensis (46.6%), Aspergillus niger species complex (40%), Fusarium spp. (13.3%) Furthermore, Aspergillus fumigatus species complex (13.3%) and the prevalence of other species was less than 10%. It was also found that positive fungal culture in burn patients is directly related to age, high percentage of burns, and length of hospitalization. 

Conclusion: Considering the high prevalence of fungal infection in burn patients and the identification of influential risk factors, all patients should be examined for fungal infection.

Keywords

Acknowledgments: The authors would like to express their gratitude to all the patients who participated in this study. We also thank the staff of Ali-ebn AbiTalib Hospital who helped us in conducting the study.

 

Availability of data and materials: The data supporting the findings of this research is available upon request from the corresponding author.

 

Conflicts of interest: The authors declare no conflict of interest.

 

Consent for publication: Not applicable.

 

Ethics approval and consent to participate: The current research is taken from the thesis approved in Zahedan University of Medical Sciences. All the experimental procedures in this study were approved by the Vice-Chancellor of Zahedan University of Medical Sciences of Iran, Zahedan (ethical code: IR.ZAUMS.REC.1401.385).The study was conducted in accordance with the principles of the Helsinki Declaration and written Informed Consent was obtained from all subjects.

 

Authors’ contribution: Study concept and design: H. A. D. and N.K. Analysis and interpretation of data: H. A.D, E. Sh. V. Drafting of the manuscript: H. A. D. Critical revision of the manuscript for important intellectual content: N.K. Statistical analysis: H. A.D. and E. Sh. V.

 

Financial disclosure: The authors have no relevant financial or non-financial interests to disclose.

 

Open Access Policy: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/

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Razavi International Journal of Medicine
Volume 12, Issue 4
November 2024
Pages 49-56

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