Evidence-based Non-drug Interventions in the Management of the Psychological Consequences of the Prevalence Covid-19: A Systematic Review

Document Type : Review Article/ Systematic Review Article/ Meta Analysis


1 Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Nursing, School of Nursing, North Khorasan University of Medical Sciences, Bojnurd, Iran


Background: Patients of Covid-19 are susceptible to suffering of psychological disorders such as anxiety, worry, fear, hopelessness, confusion, insomnia and depression.

Objectives: The present study aimed to reviewing Evidence-based non-drug interventions in the management of the psychological consequences of the prevalence covid 19.

Methods: The present systematic review article was conducted by searching and screening related studies on databases of Scopus, Cochrane, Library, Web of Science, PubMed, Embase, in accordance with the PICO scale and PRISMA guidelines during the prevalence covid 19.

Results: Of the eight selected papers, two were in children and six in adults. In patients with a definitive diagnosis of COVID-19, a significant effect of internet-based integrated intervention was shown to reduce depression and anxiety (P<0.001). Online psychoeducational interventions resulted in a significant difference in increasing resilience (P=0.04) and reducing perceived stress of patients (P=0.01). Jacobson’s relaxation technique intervention in COVID-19 patients indicated statistically significant difference in improving quality of sleep and decreases anxiety (P<0.001). The results of respiratory rehabilitation interventions and stretching exercises in COVID-19 patients were associated with improved pulmonary function tests, a significant increase in quality of life scores, and a significant decrease in depression and anxiety scores. Digital cognitive behavioral therapy significantly reduced depression and stress (P<0.001).

Conclusion: Psychological intervention can decrease depression and anxiety in healthy and patients of COVID-19 during a disease outbreak. Therefore, different psychological approaches can be effective in reducing anxiety during this stressful period.

Keywords: COVID-19, Evidence-based Practice, Non-drug interventions, Psychological Distress, Systematic review