Choroidal Metastasis from Breast Cancer in a Young Male Patient, Case Report

Document Type : Case Report/Series


MD, Eye research center, Mashhad University of Medical Sciences, Mashhad, Iran


Background: To report an uncommon case of choroidal metastasis caused by male breast cancer.
Case report: A 35-year-old gentleman presented with decreased visual acuity of left eye for about 6 months. The patient had a history of infiltrating breast carcinoma. The patient underwent a mastectomy, chemotherapy, and radiation therapy for the cancer four years ago. He was under oral medical therapy with tamoxifen. Ophthalmoscopic examination, B-scan ultrasonography, Fundus autofluorescence, Macular Optical Coherence Topography and other imaging were characteristics of metastatic choroidal tumor. Systemic investigations disclosed advanced metastatic disease. Radiotherapy is the preferred treatment for alleviating the symptoms. he received six cycles of systemic chemotherapy every three weeks with Cyclophosphamide, Methotrexate, and 5-fluorouracil. 6 months after treatment the patients BCVA increased to 4/10, and there was a reduction observed in the size of the choroidal metastasis.
Conclusion: In situations involving choroidal metastasis, it is important to consider the possibility of breast cancer as the primary cancer. We report this case to highlight this unusual source of choroidal metastasis, in males.
 Keywords: Choroid Diseases, Male Breast Neoplasm, Male Breast Carcinoma, Neoplasm metastasis