Comparison of the Effectiveness of Dialectical Behavior Therapy and CompassionFocused Therapy on Blood Cortisol and Serotonin Levels in Drug Abusers

Document Type : Original Article

Authors

1 Department of Nursing, School of Nursing and Midwifery, Torbat Heydariyeh Univercity of Medical Sciencees, Torbat Heydariyeh, Iran

2 Assistant Professor, Department of Psychology, Kashmar Branch, Islamic Azad University, Kashmar, Iran

3 Assistant Professor, Department of Psychology, Quchan Branch, Islamic Azad University, Quchan, Iran

4 Associate Professor, Department of Psychology, Neyshabur Branch, Islamic Azad University, Neyshabur, Iran

Abstract

Background and Aims: This study aimed to compare the efficacy of dialectical behavioral therapy (DBT) and compassion-focused therapy (CFT) on the blood cortisol and serotonin levels in drug abusers.

Materials: This quasi-experimental study was conducted based on a pretest-posttest control group design. The statistical population consisted of all male drug abusers who were referred to the Adult Drug Abuse Clinic of Torbat-e-Heydariyeh, Iran, during 2018. In total, 60 cases were selected through simple random sampling and subsequently divided into two experimental (DBT, CFT) and one control group. Afterward, the experimental group participated weekly in 90-min training sessions for 10 weeks. On the other hand, the control group was on the waiting list and received no training. Afterward, the data were collected using a demographic characteristic form, as well as in vitro serum test of cortisol and serotonin levels before and after the intervention. Eventually, the data were analyzed in SPPS software (version 24) using Multivariate analysis of covariance (MANCOVA).

Results: The results of MANCOVA revealed that self-control and blood cortisol had a significant effect on post-test in both DBT and CFT groups (P<0.005). However, given the mean differences, CFT showed more significant effects on the blood cortisol and serotonin levels, compared to DBT.

Conclusion: According to the findings, both DBT and CFT were effective in the reduction of cortisol and elevation of blood serotonin in drug abusers; however, CFT was more effective than DBT.

Keywords

Open Access Policy: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/

References

1.Vsevo1ozhskaya OA, Anthony JC. Transitioning from First Drug Use to Dependence Onset: Illustration of a Multiparametric Approach for Comparative EpidemiologyNeuropsychopharmacology. 2016;41(3):869-76.
https://doi.org/10.1038/npp.2015.213
PMid:26174595 PMCid:PMC4707832
 
2. Lotfi Kashani F, Mojtabai M, Alimehdi M. Comparison of the Effectiveness of Cognitive behavior Therapy, Methadone therapy, and the Combination Method on Reducing Depression in Addicts. Knowledge & Rerearch in Applide Psychology Journal. 2013;14(4):19-26.
 
3. Salimi S.H, Haghnazari A., Ahmadi-Tahour- Soltani M., Zohre-vand M. The Effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) on Drug Craving in Heroin Addicts Treated by Methadone Maintenance. Journal of Clinical Psychology. 2016; Volume 8 , Number 2 (30): 23-31.
 
4. Aguilar R , Jimenez M , Alvero-Cruz J R. Testosterone, cortisol and anxiety in elite field hockey players. Physiology & behavior.2013;119:38-42.
https://doi.org/10.1016/j.physbeh.2013.05.043
PMid:23743274
 
5. Buckingham JC. Glucocorticoids: exemplars of multi‐tasking. British journal of pharmacology.2006;147(S1):S258-S68.
https://doi.org/10.1038/sj.bjp.0706456
PMid:16402112 PMCid:PMC1760726
 
6.Lee BK , Glass TA , Mcatee MJ , Wand GS , Bandeen-Roche K , Bolla KI , Schwartz BS. Associations of salivary cortisol with cognitive function in the Baltimore memory study. Archives of general psychiatry.2007;64(7):810-818.
https://doi.org/10.1001/archpsyc.64.7.810
PMid:17606815
 
7.Ehrlenspiel F, Strahler K. Psychoneuroendocrinology of sport and exercise: Foundations, markers, trends:Routledge.;2012:154-156.
https://doi.org/10.4324/9780203133743
PMid:22946898
 
8.Dinas P, Koutedakis Y, Flouris A. Effects of exercise and physical activity on depression. Irish Journal of Medical science. 2011;180:319-25.
https://doi.org/10.1007/s11845-010-0633-9
PMid:21076975
 
9. Keogh E, Bond FW, Flaxman PE. Improving academic performance and mental health through a stress management intervention: outcomes and mediators of change. Behav Res Ther. 2006;44(3):339-57.
https://doi.org/10.1016/j.brat.2005.03.002
PMid:15890314
 
10.Fink KB, Gothert M. 5-HT receptor regulation of neurotransmitter release. Pharmacological Reviews 2007;59:360-417.
https://doi.org/10.1124/pr.59.07103
 
11. Kirby L, Zeeb F, Winstanley C. Contributions of serotonin in addiction vulnerability. Neuropharmacology. 2011;61:421-32.
https://doi.org/10.1016/j.neuropharm.2011.03.022
PMid:21466815 PMCid:PMC3110503
 
12.Khantzian E. The self-medication hypothesis of substance use disorders: a reconsideration and recent applications. Harward Review Psychiatry.1997;4(5):231-244.
https://doi.org/10.3109/10673229709030550
PMid:9385000
 
13.Dimeff LA, Linehan MM. Dialectical behavior therapy for substance abuser. Addict Sci Clin Pract. 2008;4 (2):39-47.
https://doi.org/10.1151/ascp084239
PMid:18497717 PMCid:PMC2797106
 
14.Aliloo M, Sharifi MA. Behavior therapy for borderline personality disorder. First printing, Tehran: Tehran University Counselling Center: 2011.
 
15.Linehan M. M. Cognitive-behavioural treatment of borderline personality disorder. New York:1993; Guilford Press.
 
16.Davison G.C, Neal J.M, Kring A.M. Abnormal Psychology. Translated to Persian by: Dehestani M. Vol. 1. 4th ed. Tehran: Virayesh; 2004.
 
17.Brooks M, Kay-Lambkin F, Bowman J, Childs S. Self-compassion amongst clients with problematic alcohol use Mindfulness.2012;3(4):308-317. doi: org/10.1007/s12671-012-0106-5.
https://doi.org/10.1007/s12671-012-0106-5
 
18.Rockliff H, Gilbert P, McEwman K, Lightman S, Glover D. A pillot exploration of heart rate variability and salivary cortisol reponse to compassion focuse imagery . journal of clinical neuroprychitry.2008;5:132-139.
 
19.Wills F. Mindfulness and commit ment Therapy Approach to Mindfulness and Psychology. Oakland, CA :New Harbinger; 2009.
 
20. Esnaasharan S, Yazdkhasti F, Oreyzi HR. Comparison of the Effectiveness of Psychodrama and Dialectical Behavioral Therapy in Emotion Regulation and Distress Tolerance among the Women under Abstinence. Quarterly Journal of Research on Addiction. 2018;12(45):247-264.
 
21.Nadimi M. On the Effectiveness of Group Dialectical Behavior Therapy in the Enhancement of Distress Tolerance and Emotional Regulation in Substance Abusers. Quarterly Journal of Research on Addiction. 2016; 9(36):141-160.
 
22. Aghasi A, Atashpour SH. The Impact of Dialectical Behavior Therapy - based Intervention on Craving Men with Addiction Disorders (opioid - methamphetamine). Community Health journal. 2016;10(2):11-23.
 
23.Haljin , Whitburne; Translation by Seyyed Mohammadi Y. Psychological Pathology. 7th edit. Tehran: Ravan Publishing.2014:152-4.
 
24. Kirschbaum C, Wichman S, Lorenz T & Petrowski. KEffects of the cortisol stress response on the psychotherapy outcome of panic disorder patients.2017; 77(2): 9-17.
https://doi.org/10.1016/j.psyneuen.2016.11.030
PMid:27987430
 
25. Hsiao FH, Jow GM, Lai YM, Chen YT, Wang KC, Ng SM, etal. The long-term effects of psychotherapy added to pharmacotherapy on morning to evening diurnal cortisol patterns in outpatients with major depression. Psychother Psychosom. 2011; 80(3):166-72.
https://doi.org/10.1159/000321558
PMid:21389753
 
26. Samadi H, Hoseini F, Bidaki R . The Effectiveness of 6-Week Mindfulness Training on Shooter's Salivary Cortisol Concentration and Sport Performance. Jurnal of sabzevar university of medical sciences.2016; 23(4),11-22.
 
27. Naghi Nasab A, Ardahi F, Karami A , Javan M, Seifi M. Effectiveness of body psychotherapy technique on stress and salivary cortisol level in high school girl students. Journal of Gorgan University of Medical Sciences.2014;16(4),7-13.
 
28.Romanelli RJ, Wu FM, Gamba R, Mojtabai R, Segal JB.Behavioral therapy and serotonin reuptake inhibitor pharmacotherapy in the treatment of obsessive-compulsive disorder: a systematic review and meta-analysis of head-to-head randomized controlled trials.International Joranal of Methods in Psychiateric Rerearch.2014; 31(8): 617-716.
https://doi.org/10.1002/da.22232
PMid:24390912
 
29. Soetrisno S, Sri S, Supriyadi H. R, Muhamad N. Effect of cognitive behavioral therapy for serotonin levels, depression score and quality of life in scervical cancer patients.Folia Medica Indonesiana Journal.2016; 52(3), 231-234.
https://doi.org/10.20473/fmi.v52i3.5457
 
30.Neff kD, Germer CK. A pilot study and randomized controlled trial of the mindful self-compassion program.. J Clin Psychol. 2013;69(1):28-44. doi: 10.1002/jclp.21923. [PubMed: 23070875].
https://doi.org/10.1002/jclp.21923
PMid:23070875
 
31.Gilbert P. Compassion focused therapy: Distinctive features. New York, NY: Routledge/Taylor & Francis Group. 2010.
https://doi.org/10.4324/9780203851197
 
32.Goss K, Allan S. Compassion focused therapy for eating disorders. International Journal of Cognitive Therapy (CFT-E). 2014;53(1):62-77. doi: 10.1111/bjc.12039. [PubMed: 24588762].
https://doi.org/10.1111/bjc.12039
PMid:24588762
 
33.Lowens I. Compassion focused therapy for people with bipolar disorder. International Journal of Cognitive Therapy. 2010;3(2):172-185.
https://doi.org/10.1521/ijct.2010.3.2.172
 
34.Vakili Y, Gharaee B, Habibi M. Acceptance and Commitment Therapy, Selective Serotonin Reuptake Inhibitors and Their Combination in the Improvement of Obsessive-Compulsive Symptoms and Experiential Avoidance in Patients With Obsessive-Compulsive Disorder,Iranian Journal of Psychiatery and Bihaviorl Science(IJPBS).2015; 9(2), e845. 37(1), 37-42.
https://doi.org/10.17795/ijpbs845
 
35.Zeidan F, Gordon NS, Merchant J, Goolkasian P.The effects of brief mindfulness meditation training on experimentally induced pain.2010; 11(3):199-209.
https://doi.org/10.1016/j.jpain.2009.07.015
PMid:19853530
 
36.Zamani N, Farhadi M, Jamiliyan H , Habibi M. Effectiveness of Group Dialectical Behavior Therapy (Based on Core Distress Tolerance and Emotion Regulation Components) on Expulsive Anger and Impulsive Behaviors. Journal of Arak University of Medical Sciences. 2015; 17 (11), 53-61.
 
37.Basharpoor S, Mohammadi N, Asadi-Shishegaran H. The effectiveness of cognitive self-compassion training on craving, dependence severity and cognitive flexibility in substance dependent individuals. Journal of Clinical Psychology. 2017;9(3):93-103.
 
38.Miri M. A . Sociology of Addiction. Tehran: Boshra Publications;2010:135-6.
Razavi International Journal of Medicine
Volume 9, Issue 1
January 2021
Pages 14-20

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