Frequency of Methylphenidate (Ritalin) Consumption and its Associated Factors in Medical Students

Document Type : Original Article

Authors

1 Community Medicine specialist, Community Medicine Department, School of Medicine, Mashhad University of Medical sciences, Mashhad, Iran

2 Assistant Professor of Community Medicine, Community Medicine Department, School of Medicine, Mashhad University of Medical sciences, Mashhad, Iran

Abstract

Background: Methylphenidate or Ritalin is an amphetamine derivative and a central nervous system (CNS) stimulant that is chemically similar to cocaine. A lot of reports have been made on Ritalin abuse.

Objectives: This study aimed to determine the relative frequency of Ritalin consumption and its associated factors among medical students in different steps at Mashhad University of Medical Sciences.

Methods: Using stratified random sampling, this descriptive analytical study was conducted on medical students in different steps at Mashhad University of Medical Sciences in 2015. The checklist included the subjects' background information, and also the questions associated with the frequency of Ritalin consumption and its underlying causes. Independent sample t-test was used to analyze the quantitative variables with normal distribution, and Chi-square test or Fisher's exact test to analyze the qualitative variables. However, Kruskal-Wallis and Mann-Whitney were applied as non- parametric tests to analyze the quantitative variables with non-normal distributions.

Results: This study was conducted on 340 medical students in different steps, and the response rate was reported as 91%. The frequency of Ritalin consumption among students was 17.3%. The excessive consumption of Ritalin by medical students was observed within the exams period (83%); smoking cigarette was reported in 75.5% of Ritalin user students and drug addiction in 20.8%. There was a significant difference in Ritalin consumption between the students living on- campus or off- campus and those living with their spouse or parents [OR (95% CI) = 0.5 (0.27-0.93)]; however, the higher consumption of Ritalin was reported in the first group. Moreover, a significant difference was revealed in Ritalin consumption between non-smoking students and smoking ones [OR (95% CI) = 40.34 (18.34-88.72)].

Conclusion: Regarding the prevalence of Ritalin consumption along with smoking cigarette and addiction to drugs among the students living on-campus, immediate preventive interventions are required for the people in the same age group who are living together in social environment as well as students at risk of more damages due to the abuse of such medications.

Keywords

Open Access Policy: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/

References

1.Brunton L, Lazo J, Parker K. Goodman and Gilman are the pharmacological basis of therapeutics. 11th ed. New York: The Taherani HJ et al. 16 Razavi Int J Med. 2018; 6(3):e59408. McGraw-Hill Companies; 2006.
 
2. Ghaffarinejad A, Kheradmand A. Reporting a case of injecting methylphenidate (ritalin) tablets, intensified symptoms of schizoph-renia or induce separate mental disorder? Addict Health. 2009;1(2):111-4. [PubMed: 24494093].
 
3. Morton AW, Stockton GG. Methylphenidate abuse and psychiatric side effects. Prim Care Companion J Clin Psychiatry. 2000;2(5):159-64. [PubMed: 15014637].
https://doi.org/10.4088/PCC.v02n0502
PMid:15014637
 
4. Low KG, Gendaszek AE. Illicit use of psycho stimulants among college students: a preliminary study. Psychol Health Med. 2002;7(3):283-7..
https://doi.org/10.1080/13548500220139386
 
5. Babcock BA, Byrne T. Student perceptions of methylphenidate abuse at a public liberal arts college. J Am Coll Health. 2000;49(3):143-5. [PubMed: 11125642].
https://doi.org/10.1080/07448480009596296
PMid:11125642
 
6. Teter CJ, McCabe SE, Boyd CJ, Guthrie SK. Illicit methylphenidate use in an undergraduate student sample: prevalence and risk factors. Pharmacotherapy. 2003; 23(5):609-17. [PubMed: 12741435].
https://doi.org/10.1592/phco.23.5.609.34187
PMid:12741435
 
7. Bogle KE, Smith BH. Illicit methylphenidate use: a review of prevalence, availability, pharmacology, and consequences. Curr Drug Abuse Rev. 2009;2(2):157-76. [PubMed: 19630746].
https://doi.org/10.2174/1874473710902020157
PMid:19630746
 
8. Barrett S, Darredeau C, Bordy LE, Pihl RO. Characteristics of methylphenidate misuse in a university student sample. Can J Psychiatry. 2005;50(8):457-61. [PubMed: 16127963].
https://doi.org/10.1177/070674370505000805
PMid:16127963
 
9. Fatemi N, Khoshnavaye Foomani F, Behbahani N, Hosseini F. Assertiveness skill and use of Ecstasy among Iranian adolescents. Quart J Fundam Mental Health. 2007;10(40):265- 72. [Persian]
 
10. Kaplan H, Sadock B, James B. Summary of psychiatry. Trans: Pourafkari N. Tehran: L. Shahr-e-Ab; 2003. P. 534-88.
 
11. Gouzoulis-Mayfrank E, Daumann J, Tuchtenhagen F, Pelz S, Becker S, Kunert HJ, et al. Impaired cognitive performance in drug free users of recreational ecstasy (MDMA). J Neurol Neurosurg psychiatry. 2000;68(6):719-25. [PubMed: 10811694].
https://doi.org/10.1136/jnnp.68.6.719
PMid:10811694 PMCid:PMC1736948
 
12. Solowij N, Hall W, Lee N. Recreational MDMA use in Sydney; a profile of ecstasy user and their experiences with the drug. Br J Addict. 1992;87(8):1161-72. [PubMed: 1354992].
https://doi.org/10.1111/j.1360-0443.1992.tb02003.x
PMid:1354992
 
13. Ataei M, Hosseini N, Ahmadi JT, Jalilian F, Mirzaei AM, Eslami AA, et al. Application of prototype/willingness model in describe ritalin abuse behavior among college students. Health Syst Res. 2014;10(2):335-44.
 
14. Khademi L, Shariat SV. Prevalence of nonmedical use of methylphenidate (Ritalin) in residents of Tehran university of medical sciences and their attitude toward methylphenidate use. Iran J Psychiatry Clin Psychol. 2013;19(1):20-7.
 
15. Novak SP, Kroutil LA, Williams RL, Van Brunt DL. The nonmedical use of prescription ADHD medications: Results from a national internet panel. Subst Abuse Treat Prev Policy. 2007;2:32. [PubMed: 17974020].
https://doi.org/10.1186/1747-597X-2-32
PMid:17974020 PMCid:PMC2211747
 
16. Arria AM, Wish ED. Nonmedical use of prescription stimulants among students. Pediatr Ann. 2006;35(8):565-71. [PubMed: 16986451].
https://doi.org/10.3928/0090-4481-20060801-09
PMid:16986451 PMCid:PMC3168781
 
17. Habibzadeh A, Alizadeh M, Malek A, Maghbooli L, Shoja MM, Ghabili K. Illicit methylphenidate use among iranian medical students: prevalence and knowledge. Drug Des Dev Ther. 2011;5:71-6. [PubMed: 21340040].
https://doi.org/10.2147/DDDT.S13818
PMid:21340040 PMCid:PMC3038997
 
18. Valipour M, Zivdar M, Amin M, Bazvand S, Saki M, Omidifard Z. Prevalence and predisposing factors for substance abuse among students. Aflak. 2011;5(14-15):63-7. [Persian]
 
19. Eslami AA, Jalilian F, Ataee M, Alavijeh MM, Mahboubi M, Afsar A, et al. Intention and willingness in understanding Ritalin misuse among Iranian medical college student: A crosssectional study. Glob J Health Sci. 2014;6(6):43-53. [PubMed: 25363098].
https://doi.org/10.5539/gjhs.v6n6p43
PMid:25363098 PMCid:PMC4825534
 
20. Habibzadeh A, Alizadeh M, Malek A, Maghbooli L, Shoja MM, Ghabili K. Illicit methylphenidate use among iranian medical students: prevalence and knowledge. Drug Des Dev Ther. 2011;5:71-6. [PubMed: 21340040].
https://doi.org/10.2147/DDDT.S13818
PMid:21340040 PMCid:PMC3038997
 
21. Rezahosseini O, Rpphbakhsh A, Tavakolian V, Assar S. Drug abuse among university students of Rafsanjan, Iran. Iran J Psychiatry Behav Sci. 2014;8(2):81-5. [PubMed: 25053961].
 
22. Barati M, Allahverdipour H, Jalilian F. Prevalence and predictive factors of psychoactive and hallucinogenic substance abuse among college students. J Fundam Mental Health. 2012;13(4):374-83. [Persian]
 
23. Taremian F, Bolhari J, Pairavi H, Ghazi Tabatabaeii M. The prevalence of drug abuse among university students in Tehran. Iran J Psychiatry Clin Psychol. 2008;13(4):335-42. [Persian]
 
24. Jalilian F, Karami-Matin B, Mirzaei Alavijeh M, Ataee M, Mahboubi M, Motlagh F, et al. Prevalence and factor related to ritalin abuse among Iranian medical college student: an application of theory of planned behavior. Terapevticheskii Arkhiv. 2013;85(4s):22-7.
 
25. Finger G, Silva ER, Falavigna A. Use of methylphenidate among medical students: a systematic review. Rev Assoc Med Bras. 2013;59(3):285-9.
https://doi.org/10.1016/j.ramb.2012.10.007
PMid:23680277
 
26. McCabe SE, Teter CJ, Boyd CJ, Guthrie SK. Prevalence and correlates of illicit methylphenidate use among 8th, 10th, and 12th grade students in the United States, 2001. J Adolesc Health. 2004;35(6):501-4.
https://doi.org/10.1016/S1054-139X(04)00067-9
PMid:15581530
 
27. Moore DR, Burgard DA, Larson RG, Ferm M. Psychostimulant use among college students during periods of high and low stress: An interdisciplinary approach utilizing both selfreport and unobtrusive chemical sample data. Addict Behav. 2014;39(5):987-93. [PubMed: 24561016].
https://doi.org/10.1016/j.addbeh.2014.01.021
PMid:24561016
 
28. Ansari-Moghaddam A, Rakhshani F, Shahraki-Sanavi F, Mohammadi M, Miri-Bonjar M, Bakhshani NM. Prevalence and patterns of tobacco, alcohol, and drug use among Iranian adolescents: a meta-analysis of 58 studies. Children Youth Serv Rev. 2016;60:68-79.
https://doi.org/10.1016/j.childyouth.2015.11.018
 
29. Teter CJ, McCabe SE, LaGrange K, Cranford JA, Boyd CJ. Illicit use of specific prescription stimulants among college students: prevalence, motives, and routes of administration. Pharmacotherapy. 2006;26(10):1501-10. [PubMed: 16999660].
https://doi.org/10.1592/phco.26.10.1501
PMid:16999660 PMCid:PMC1794223
Razavi International Journal of Medicine
Volume 6, Issue 3
July 2018
Pages 36-41

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