Study of hs-CRP Level in Prisoners in Mashhad and Their Relation to Demographic Factors

Document Type : Original Article

Authors

1 MD, specialist in Community Medicine, Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

2 MD, Department of Community Medicine, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran

3 PHD, Immunology Research Center, Inflammation and Inflammatory Diseases division, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran

4 MSC, Immunology Research Center, Inflammation and Inflammatory Diseases division, Medical School, Mashhad University of Medical Sciences, Mashhad, Iran

5 MD, Pathologist, Razavi Cancer Research Center, Razavi Hospital, Imam Reza International University, Mashhad, Iran

Abstract

Background: Prisoners are a certain part of the population. Prisoners are kept in a closed environment for a long period of time and are prone to various diseases. Inflammatory biomarkers, including hs-CRP, are new risk factors for cardiovascular disease.

Objectives: The aim of this study was to compare hs-CRP levels in male and female prisoners and investigate the relationship between hs-CRP levels with related factors.

Methods: In this cross-sectional study, 316 prisoners in Mashhad Prison were investigated. A blood sample (7ml) was taken from each subject. Enzyme-linked immunosorbent assay (ELISA) technique was used to measure serum levels of highsensitivity C-reactive protein (hs-CRP). Descriptive statistics, chi-squared test, T-test, Pearson and Spearman’s correlation coefficients were used. P<0.05 was considered to be the level of significance.

Results: 316 prisoners were investigated of whom 211 (66.8%) were male and 105 (33.2%) were female. Mean hs-CRP level was 5.72±7.93 μg/ml in men and 7.48±8.39 in women. The difference between the two genders were statistically significant (p<0.001). The mean hs-CRP level was significantly higher in prisoners who did injection drug use compared to those who inhaled or consumed drugs (p<0.001). A significant correlation was observed between age, systolic blood pressure, frequency of imprisonment, height and BMI and hs-CRP levels.

Conclusion: Since hs-CRP is an important biomarker for non-communicable diseases, considering these factors and other risk factors for chronic diseases in the high-risk and vulnerable groups of prisoners, prevention and control measures can be planned by this group of people.

Keywords

Open Access Policy: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/

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Razavi International Journal of Medicine
Volume 6, Issue 2
April 2018
Pages 15-19

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