Eccentricity Index Identifies the Severity of Left to Right Shunt in PatientsWith SecundumType Atrial Septal Defect

Authors

1 Razavi Cancer Research Center, Razavi Hospital, Imam Reza International University, Mashhad, Iran

2 Cardiologist, Cardiovascular Center, Research and Education Department, Razavi Hospital,Mashhad, IR Iran

3 Associate Professor of Cardiology, Razavi Hospital,Mashhad University of Medical Sciences,Mashhad, IR Iran

Abstract

Abstract Background: One of the inclusion criteria for applying atrial septal defect (ASD) closing procedure is an increased pulmonary-to- systemic blood flow ratio (Qp/Qs). Eccentricity index (EI) is associated with ventricular dysfunction in patients with pulmonary hypertension. Objectives: As ASDpatients have overload volume and pressure in their pulmonary arteries,we tried to test this hypothesis if EI and Qp/Qs ratio are possibly associated. Patients andMethods: This study is a correlation study. 64 patientswith primary diagnosis of secundumtype ASD enrolled in this study and echocardiography was performed for all of them. Data were analyzed by SPSS as well as descriptive and statistical tests. Results: Bivariate correlation test showed that therewas a positive and significant association betweenQp/Qs ratio and EI (r = 0.502, P = 0.001). Linear regression analysis showed that there was a linear association between Qp/Qs ratio and EI (Beta = 1.765, P = 0.001). Conclusions: We found that EI and Qp/Qs ratio are significantly and positively associated and Qp/Qs ratio can be easily estimated bymeasuring EI in secundumtype ASD patients.

Keywords

References

  1. 1.Krasuski RA. When and how to fix a ’hole in the heart’: approach to ASD and PFO. Cleve Clin J Med. 2007;74(2):137–47. [PubMed: 17333641].

    1. Ryan T, Petrovic O, Dillon JC, Feigenbaum H, Conley MJ, Armstrong WF. An echocardiographic index for separation of right ventricular volume and pressure overload. J Am Coll Cardiol. 1985;5(4):918–27. [PubMed: 3973294].
    2. Raymond RJ, Hinderliter AL, Willis PW, Ralph D, Caldwell EJ, Williams W, et al. Echocardiographic predictors of adverse outcomes in primary pulmonary hypertension. J Am Coll Cardiol. 2002;39(7):1214–9. [PubMed: 11923049].
    3. Currie PJ, Seward JB, Chan KL, Fyfe DA, Hagler DJ, Mair DD, et al. Continuous wave Doppler determination of right ventricular pressure: a simultaneous Doppler-catheterization study in 127 patients. J Am Coll Cardiol. 1985;6(4):750–6. [PubMed: 4031289].
    4. Kircher BJ, Himelman RB, Schiller NB. Noninvasive estimation of right atrial pressure from the inspiratory collapse of the inferior vena cava. Am J Cardiol. 1990;66(4):493–6. [PubMed: 2386120]. 6. Quinones MA, Otto CM, Stoddard M, Waggoner A, Zoghbi WA, Doppler Quantification Task Force of the N, et al. Recommendations for quantification of Doppler echocardiography: a report from the Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. J Am Soc Echocardiogr. 2002;15(2):167–84. [PubMed: 11836492].
    5. Lopez-Candales A, Rajagopalan N, Kochar M, Gulyasy B, Edelman K. Systolic eccentricity index identifies right ventricular dysfunction in pulmonary hypertension. Int J Cardiol. 2008;129(3):424–6. doi: 10.1016/j.ijcard.2007.06.057. [PubMed: 17692406].
    6. Nielsen JC, Kamenir SA, Ko HS, Lai WW, Parness IA. Ventricular septal flattening at end systole falsely predicts right ventricular hypertension in patients with ostium primum atrial septal defects. J Am Soc Echocardiogr. 2002;15(3):247–52. [PubMed: 11875388].
Razavi International Journal of Medicine
Volume 4, Issue 2
April 2016
Pages 1-3

Files

Share

How to cite

Statistics