Correlation Between Some Risk Factors and the Incidence of Diarrhea Outbreak in Kosar Industrial Estate, A Case-Control Study in 2013

Document Type : Original Article


1 Gonabad University of Medical Sciences, Gonabad, IR Iran

2 Medicine School, Gonabad University of Medical Sciences, Gonabad, IR Iran

3 Department of Basic Sciences, School of Paramedical Sciences, Gonabad University of Medical Sciences, Gonabad, IR Iran



Background: The most important diarrheal disease of the year warm seasons is cholera with Vibrio cholera bacteria that some cases are observed in the country every year. Objectives: The purpose of this study was to identify the outbreak factors of diarrheal disease and prevention ways of its mortality rate among Gonabad city workers. Patients and Methods: This study is a case-control study conducted in 29 June 2013 to 6 August 2013, followed by diarrhea outbreak occurred in Brick kilns of Kosar industrial unit in Gonabad city. The data were collected by a questionnaire from patients and healthy people. Cholera sample and Stool exam were taken from all the patients. To determine the source of disease, water microbial sampling, chlorine metering and chlorine chlorination was conducted. Results: A total of 120 workers were studied (60 cases and 60 controls) who were the same from age and sex point of view. Clinical signs observed in 60% of cases were abdominal cramping and 11.6% had nausea. Human test results showed 1 sample of Eltor ogawa serotype and 4 Nag strains. No significant differentiation was observed in hand washing between the patients and the healthy ones (P = 0.15). The risk factor of using from water storage was 3 times more in case than the control group. Conclusions: Health disobedience and neglect of local residents were the causes of water pollution that was controlled with preventional measures, with performing daily chlorination of Brick kilns drinking water and diarrheal disease treatment of the patients.