Eccentricity Index Identifies the Severity of Left to Right Shunt in PatientsWith SecundumType Atrial Septal Defect


1 Razavi Cancer Research Center, Razavi Hospital, Imam Reza International University, Mashhad, Iran

2 Cardiologist, Cardiovascular Center, Research and Education Department, Razavi Hospital,Mashhad, IR Iran

3 Associate Professor of Cardiology, Razavi Hospital,Mashhad University of Medical Sciences,Mashhad, IR Iran



Abstract Background: One of the inclusion criteria for applying atrial septal defect (ASD) closing procedure is an increased pulmonary-to- systemic blood flow ratio (Qp/Qs). Eccentricity index (EI) is associated with ventricular dysfunction in patients with pulmonary hypertension. Objectives: As ASDpatients have overload volume and pressure in their pulmonary arteries,we tried to test this hypothesis if EI and Qp/Qs ratio are possibly associated. Patients andMethods: This study is a correlation study. 64 patientswith primary diagnosis of secundumtype ASD enrolled in this study and echocardiography was performed for all of them. Data were analyzed by SPSS as well as descriptive and statistical tests. Results: Bivariate correlation test showed that therewas a positive and significant association betweenQp/Qs ratio and EI (r = 0.502, P = 0.001). Linear regression analysis showed that there was a linear association between Qp/Qs ratio and EI (Beta = 1.765, P = 0.001). Conclusions: We found that EI and Qp/Qs ratio are significantly and positively associated and Qp/Qs ratio can be easily estimated bymeasuring EI in secundumtype ASD patients.