Re-Bleeding in Patients With Cirrhosis: Evaluation of Esophageal and Gastric Variceal Bleeding and Their Relationship With a Model for the End-Stage Liver Disease (MELD) Score and Child-Pugh Score


1 Department of Emergency Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran

2 Department of Internal Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran



Background: Variceal bleeding is one of the leading causes of mortality in patients with cirrhosis. Child-pugh (CP) score and model for the end-stage liver disease (MELD) score systems are the two main methods for predicting the complications and mortality of cirrhosis; however, none of these methods has been definitively superior to the other. Objectives: In this study we compare and determine these scores in both groups of patients with esophageal and gastric variceal bleeding. Furthermore, re-bleeding rate in these two groups will be studied and compared. Patients and Methods: In this cohort study all patients with upper gastrointestinal bleeding chief complaint referred to the emergency ward of Imam Reza Hospital, Mashhad, Iran from April 2012 to April 2013 were enrolled. Then patients distributed in to two groups of esophageal and gastric variceal bleeding based on the endoscopic results. Finally the relationship between different clinical and paraclinical variables and bleeding rate in these two groups compared by means of Child-Pugh and MELD scores. T-test, χ2 test, and the Kruskal-Wallis test were used for analysis by means of SPSS 17.0 for Windows. Data were expressed as mean ± standard deviation and P